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How Much Protein to Eat on a GLP-1 and Why It Matters We know that weight loss, whether from medication or lifestyle alone, almost always comes with some loss of lean mass
The article says tesofensine blocks the reuptake of norepinephrine, dopamine, and serotonin in the brain, while tirzepatide activates GLP-1 and GIP receptors in the gut and brain
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However: Longer-term safety data (5+ years) is still being collected Individual risk factors vary significantly Regular medical monitoring essential for ongoing safety assessment Some individuals develop side effects requiring discontinuation Long-term cardiovascular benefits observed in some trials (SELECT trial with semaglutide) Healthcare providers should regularly reassess whether continued treatment remains appropriate for individual circumstances based on ongoing benefits, risks, and patient preferences
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