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If youre concerned about alcohol dependence, consult with addiction medicine specialists or resources like CAMH (Centre for Addiction and Mental Health)

Notably, while OTUD5 cleaves several linkage types, OTUD5 mutations found in human patients with developmental disorders affect DUB activity toward K48 linkage 28

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Alcune metanalisi segnalano un possibile aumento del rischio di calcoli alla colecisti e un moderato incremento degli enzimi pancreatici, anche se il rischio di pancreatite non sembra significativamente superiore al placebo

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