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10.1186/gb-2008-9-7-r115 121 VacchinaP.Norris-MullinsB.AbengozarM

an overview of recent advances

155 Furthermore, GDH-derived NADPH is consumed to support the reductive carboxylation of -KG by IDH2, and the compensatory increase in the expression of GDH1 or GDH2 promote the growth of IDH-mutant glioma cells