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The term has emerged in informal community discussion as a shorthand for "the third generation of GLP-class peptides" specifically retatrutide, which acts on three receptors (GLP-1, GIP, and glucagon)
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It started as a treatment for type 2 diabetes, but once its weight loss effects became widely known, the floodgates opened
Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice
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