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Key contraindications may include active cancer-related conditions, a history of pancreatitis, pregnancy, breastfeeding, and individual intolerance

For managing nausea specifically, the following strategies may help: Eating cold or room-temperature foods , which tend to have less aroma and are often better tolerated than hot meals Ginger-based foods or drinks (for example, ginger tea or ginger biscuits) there is modest evidence supporting ginger's role in reducing nausea [24] [25] Resting upright for 3060 minutes after eating to support gastric transit Avoiding strong food smells during preparation if nausea is prominent Constipation is another common side effect associated with GLP-1based therapies