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Exenatide-PD3, reported in The Lancet in early 2025, was the largest and longest trial of a GLP-1R agonist in Parkinsons disease: 194 patients, once-weekly exenatide, 96 weeks

The results are somewhat consistent with the earlier study on Egyptian C

Second, with any short-term agent, durability is the weak point short-term weight loss is common, but the majority of patients regain weight over the following years unless the underlying behavior and physiology are addressed

Propionyl-L-Carnitine with Glycine combines a low dietary dose of PLC with the amino acid glycine supplement, which itself has beneficial effects on heart health