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Split dosing becomes valuable when single dosing produces inconsistent results, when doses above 400mcg are needed, or when evening administration fits better into lifestyle patterns
No human clinical trials have been conducted
Most people absorb enough natural B12 that they dont have to worry about additional supplements, but for those with poor nutrition, stomach problems or cancer, B12 can be hard for the body to process
No clinical data supports any administration regimen, schedule, or combination with other compounds
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