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JAK2 activation in BPC-157-treated tendon fibroblasts occurs in a time-dependent manner following growth hormone stimulation, indicating the peptide primes cells for enhanced growth factor responsiveness rather than directly activating the pathway in the absence of the endogenous ligand
PMID: 36736729 Teichman SL, et al
In clinical practice, B12 injections are administered intramuscularly, usually into the deltoid or gluteal muscle
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