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To uncover the mechanisms orchestrating the network of cell death pathways, research focuses on the identification of possible switches between distinct lethal subroutines, critically influencing the selection of a particular cell death modality acting as a connecting bridge
Methods in Molecular Biology, Vol
We therefore initiated selection on a longer gasdermin D substrate, GD_M (Ala 244Thr 284), using truncated GGS linkers to minimize the opportunity for the evolution of linker recognition
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