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Only if deficiency exists
The German Commission E recommends a daily dose of 1215 g of crude herb or 200400 mg of silymarin daily (calculated as silybin)
Shape engineering, such as rod-like versus spherical particles, can enhance membrane contact and cellular uptake, while stimuli-responsive materials (e.g., ROS- or pH-sensitive polymers) enable on-demand drug release at RIRI lesions, reducing off-target effects
The comparison between injectable and oral peptides is relevant here, as oral formulations, where available, eliminate the storage complexity of reconstituted solutions entirely, though they come with their own set of bioavailability considerations as discussed in the peptide capsules guide
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