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They report that transcript abundance changed, which is not the same claim as that a function changed, and the gap between those two statements is where most over-reading of this compound happens
Since co-treatment of UK-5099 and JMF4073 depleted dTTP pool and suppressed the growth of T315-Bcr-Abl-32D cells, we proposed that reducing GSH biosynthesis induces not only oxidative stress but also replication stress in tumor cells, which demands the synthesis of dTTP and dCTP for survival
11 In the study, the patients were adults, mostly women
Note that in a larger set of 77 human coronaviruses, a serine (S) in P4 is very common ( pro active site
