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Clinical implications GLP and GIP have implications in the following diseases and conditions: Diabetes: Type 2 diabetes is characterized by a severely reduced or absent incretin effect
It is well known that cells (particularly immune, lung, reproductive, and brain cells) function optimally when glutathione levels are in peak range
Accordingly, the two-domain ligand binding model suggests that the N-terminal part of the peptide hormones engage the TM and ECL region of the receptor leading to activation and signal transduction 13
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