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In many of these cases, altered renal function has been reversed with supportive treatment and discontinuation of potentially causative agents

At InCare, we provide compassionate care tailored to the unique challenges cancer patients face

The use of NNMT inhibitors as a potential obesity treatment has been investigated preclinically 8,9,13 , and observational clinical data suggests that increased NNMT expression and activity correlate with increased incidence of Type 2 diabetes (T2D) and risk of obesity, respectively 10,11

While previous studies have shown that CNS GABAergic neurons are necessary for the food intake- and body weight-reducing effects of GIPR agonists 5,11 , the anatomic region that underlies these effects remains unknown