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Expression of CYP1A1 and CYP1A2 in the liver and kidney of rabbits after prolonged infusion of propofol
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FIGURE 4 This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology (Valdovinos-Flores and Gonsebatt, 2012
Moreover, preclinical studies of individual peptides have not reported significant acute toxicity
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