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Stimulant-based compounds such as caffeine work by activating the central nervous system, which may temporarily increase energy expenditure and reduce appetite
However, for consistency, many studies will maintain a static dose once the target level is reached for the duration of the experiment
TORC1 is essential for NF1-associated malignancies
Additional pharmacokinetic parameters (C max , T max , t 1/2 ) were calculated from plasma TMAO and L-carnitine concentrations using R package pracma (47)
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