Interestingly, some cells treated with kanamycin and most cells treated with ciprofloxacin, but no cells treated with ampicillin, exhibited cytoplasmic condensation, a phenotype in which the cytoplasm fragments and grows denser, as manifested by the appearance of discrete, phase-light regions between phase-dark regions that grow darker (Supplementary Figs
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Based on their findings, Kannan and colleagues hypothesized that the Na + -dependent GSH transporter may be operational for uphill transport of GSH while the Na + -independent GSH transporter may be operational bidirectionally and involved in GSH efflux [37]
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