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NTZ significantly ameliorated hepatic inflammation by reducing the levels of the proinflammatory cytokines compared to the MTX group in a dose-dependent manner
(4) S Seiwerth, P Sikiric, Z Grabarevic et al
A similar scenario has in fact been reported recently in an alcoholic liver disease model in which long-term alcohol consumption activated NF-B in Kupffer cells, whereas NF-B activation in hepatocytes was inhibited 45
Managing Side Effects The combination is generally well tolerated, but most patients experience at least mild side effects in the first 8 weeks
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