semaglutide options for weight loss Trying to decide between and tirzepatide. They are both great options, just a little different depending on your goals. ✔️ We are here to help you figure out what fits you GLP-1 for Weight Loss: Shots

Clinical trials vs real-world results What the clinical trials show The landmark SURMOUNT-5 trial published in 2025 compared these medications directly at standard maximum doses: 1 Mounjaro (tirzepatide 15 mg) produced 20.2% average weight loss Wegovy (semaglutide 2.4 mg) produced 13.7% average weight loss The 6.5 percentage point difference was statistically significant This trial used the maximum approved doses at the time (Mounjaro 15 mg, Wegovy 2.4 mg) and lasted 72 weeks

(Tukey RH and Strassburg CP, Mol

That is why obese individuals tend to have abnormal hormone levels that disrupt metabolism, leading to excess body fat (1)

Walsh, N