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Mutant SOD1 forms inclusions in the presence of oxidative stress and WT SOD1 misfolds when the redox environment is dysregulated (Oeda et al., 2001)
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Lancet 383 , 11381146 (2014)
The full dose titration period takes 16 to 20 weeks for semaglutide and 20 weeks for tirzepatide, meaning maximum weight loss velocity typically begins 4 to 5 months after starting treatment
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