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We will determine if there is any interval \( \lambda \in [0,1] \) which verifies one or the other convexity inequality

chronic, maintenance of weight balance Synergy with leptin , amylin restores leptin sensitivity in obese models Synergy with CCK and GLP-1 , multi-pulse pathways of appetite suppression No tolerance , chronic administration of amylin preserves efficacy Why it matters: Lutzs review article established the scientific basis for amylin pharmacotherapy of obesity

10.1016/j.bmc.2010.11.026 Bioorg