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While this study population was specific, the magnitude of weight loss aligns with and extends the Phase 2 findings, suggesting that the 24% range is reproducible across populations at the highest dose

Examples: 1 mL, 2 mL, 2.5 mL, 3 mL, or a custom amount

Moderate obesity, with a BMI of 30 to 35, can reduce life expectancy by three years

Reported incidences in those receiving a 12mg/weekly dose of retatrutide were [21]: Nausea (45% of participants) Vomiting (19%) Constipation (16%) Diarrhea (15%) Cardiac arrhythmia (11%) Fatigue (10%) Increased pancreatic enzyme (lipase) levels (8%) Injection site reactions (8%) Liver issues in 2 participants (3%) Pancreatitis in 1 participant (2%) Both tirzepatide and retatrutide share similar contraindications, including advice against their use during pregnancy and breastfeeding