Better grounded now, but still not a forever-settled answer Sources Wilding JPH et al
The toxin resembled glucagon, a hormone that raises blood sugar, so, scientists named it glucagon-like-peptide 1, or GLP-1. In the early 2000s, we got our first medical breakthrough with GLP-1, a drug called exenatide (Byetta) approved for the treatment of type 2 diabetes
Now, with the compounders on their heels, Lilly is looking to grab their patients
( + ions, which altered pH, and the alteration of the pH led to an increase in melanin production by correcting the trafficking of tyrosinase, the enzyme that catalyzes the rate-limiting step of melanogenesis, and tyrosine-related protein-1 (TRP-1) to the proper compartments ( Figure 2A )