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It stimulates lipolysis (the breakdown of fat) and inhibits lipogenesis (the formation of fatty acids and other lipids), particularly in areas with stubborn fat deposits
Similar in vitro work showed that HGF promoted dendritic arborization in hippocampal neurons, an effect that could be blocked by NMDA receptor antagonists and was dependent on intracellular calcium and CaMKII activity [2]
Self-injectable peptides or topical cream, no clinic visits after enrollment, no pharmacy lines
It has completed Phase 3 clinical trials (the REDEFINE program) with positive results, and Novo Nordisk is expected to seek FDA approval
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