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Also, AC protected Hep3B liver cells in vitro from DEN-induced cytotoxicity, DNA damage, and reactive oxygen species (ROS) accumulation, while preventing mitochondrial membrane potential loss
In male rats exposed to electric foot shocks, levels of TRP, KYN, 3-HK, and KYNA shift dramatically across plasma and multiple brain regions, normalizing within 24 h suggesting a dynamic and time-sensitive response of KP metabolism to stress [69]
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Most users tolerate glutathione well
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