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Dual Mechanism for Insulin Resistance Tirzepatide activates both GIP and GLP-1 receptors, providing enhanced insulin sensitizationdirectly attacking the metabolic driver of PCOS with twice the firepower
Interestingly, higher incidence of diabetic retinopathy (DR) complications was noted in patients taking semaglutide (3.0%) compared to placebo (1.5%) in clinical trials, with greater risk in those with a history of DR [32]
doi: 10.1038/s41591-020-0939-8 27 ViolaAMunariFSanchez-RodriguezRScolaroTCastegnaA
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