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For the sake of completeness, we acknowledge that the current manuscript is focused on exploring microbial mechanisms potentially associated with the digestibility phenotype

Getting vitamin B12 injections to raise your B12 level to where it should be often improves symptoms like: If left untreated, vitamin B12 deficiency can lead to severe problems, including neurological (nervous system) damage that cant be reversed

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You're no longer dealing with predictable minor losses but with exponential decay