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In contrast, the protein level of PARP-1 was reduced compared with the T2DM or T2DM + sham groups

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In contrast, TgSNF2a-depleted parasites also exhibited the presence of multiple apicoplasts, but the proportion remained below 15% even after 7 days of IAA treatment (Fig

T2DM and hyperglycemia are also associated with oxidative stress from the overproduction of reactive oxygen species (ROS) and decreased efficiency of scavengers systems ( Furthermore, our lab has previously shown that individuals with T2DM have lowered levels of GSH due to decreased levels of both GCL and GSS protein compared to healthy subjects ( M