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The rate slows for physiological reasons that have nothing to do with the medication becoming less effective
NSL literature pointer PMID 3102372 L-Carnitine laboratory index [PMID: 3102372] National Science Labs indexing note for PMID 3102372: review the PubMed methods, models, and limitations before citing
21(1): 1623 Vlahos NF, Gregoriou O, Deliveliotou A, Perrea D, Vlachos A, Zhao Y,
AHK-Cu is more often seen in hair formulations
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