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The NHS guidance on vitamin B12 deficiency treatment recommends a loading course of injections first, followed by regular maintenance doses

These can include, but are not limited to, pain, redness, or swelling at the place of injection

Alpha-melanocyte stimulating hormone (-MSH): Biology, clinical relevance and implication in melanoma

Heritage and perspectives POMC and its derivatives have been discovered over nearly a century: alpha-MSH identification by Harris in the 1950s, POMC characterization by Nakanishi and Numa (Nature, 1979), cloning of the five MC1R-MC5R receptors between 1992 and 1994 (Cone, Mountjoy, Gantz teams)