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Our current understanding is that both, circulating IGF-I levels and locally produced IGF-I, contribute to the maintenance of microcirculation functional and structural integrity, increasing NO bioavailability, decreasing reactive oxygen species (ROS) production, and exerting antiinflammatory, antiapoptotic, and pro-angiogenic effects
a 20% solution reached 2.7 mg/ml versus 2.2 mg/ml for 10%
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Michael Ash
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