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A multicenter, randomized, open-label, phase 3b trial, SURMOUNT-5 was launched to compare the efficacy and safety of tirzepatide compared with semaglutide in adults with obesity or overweight without diabetes and at least 1 of the following comorbidities: hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease

Phase 2 trials demonstrated increased corneal nerve fiber area (structural nerve regeneration) in sarcoidosis SFN patients, and improved HbA1c and neuropathic symptoms in type 2 diabetes patients

Possible side effects of phentermine include dry mouth and digestive issues like nausea, vomiting, diarrhea, and constipation

With several promising early findings in lab and small clinical studies, a few of the peptide-based approaches out there are noteworthy