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Research in earlier phases or small trials include evaluation of GLP-1s for cystic fibrosis-related diabetes, polycystic ovarian syndrome (PCOS), chronic obstructive pulmonary disease (COPD), Prader-Willi syndrome (PWS), asthma, substance or alcohol use disorder, and as add-on to insulin for type 1 diabetes (T1DM)
For example, smoking, dietary habits, and microbial dysbiosis can induce chronic low-grade systemic inflammation, which not only contributes to cardiovascular diseases, diabetes, respiratory disorders, and NDDs but also increases the risk of cancer [218, 219]
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