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Limited Clinical Efficacy Due to Low Bioavailability Curcumins low bioavailability necessitates high oral doses to achieve minimal therapeutic effects, which may not be feasible or safe for long-term use [14-16]
For data-independent acquisition (DIA) liquid chromatographytandem MS (LC-MS/MS), 500 ng protein equivalent of digested peptides were analyzed using a nano-high-performance liquid chromatography coupled to MS
The idea is that by helping to regulate appetite and reduce the intense focus on food, they might indirectly improve mood and reduce symptoms of depression
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