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683 The improved mtZFNs effectively eliminated point mutations and large-scale mtDNA deletions, reducing the mutant mtDNA haplotype load below the pathogenic threshold, thereby restoring OXPHOS function and improving mitochondrial respiration

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The eluted derivatives of GSH were detected at an excitation wavelength of 340 nm and an emission wavelength of 420 nm

Pain relief was linked to improvements in clinical symptom scores and morphometric parameters of sural nerve biopsy, ie the increased fiber numbers and clusters of regenerating fibers