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For people who are not getting enough help from currently available antidepressants, this could be something that could be added to that and possibly get a better response, in the short-term, says psychiatrist Amit Anand, MD, who is also Vice-Chair for Research at the Center for Behavioral Health and Director of the Mood Disorders Program
Another tumor suppressor, retinoblastoma (Rb), can directly regulate the glutamine transporter ASCT2 ( SLC1A5 ) to reduce glutamine uptake via the transcription factor E2F3 (Reynolds et al., 2014)
The conservative 1mg starting dose allows assessment of individual tolerance before increasing