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Intranasal administration offers convenience
It's the first oral PCSK9 inhibitor ever approved a drug class that's existed only as injectables (Amgen's Repatha, Regeneron/Sanofi's Praluent, Novartis' Leqvio) since PCSK9 inhibitors reached market roughly a decade ago
Enzyme levels were expressed as nmol.minute 1 .mg of protein 1
Hypoglycemia is the most acute concern at higher doses LR3 binds the insulin receptor with sufficient affinity to lower blood glucose
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