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Notably, while AP/NTS neurons express GLP-1Rs [3, 47], inhibiting GLP-1R-expressing AP neurons does not prevent the appetite-suppressing effects of endogenously released GLP-1 [39], likely because of low amounts of GLP-1 reaching these neurons due to rapid GLP-1 degradation by the enzyme dipeptidylpeptidase IV (DPPIV) [48]
It's a hormone your body has been producing your entire life
Thus, pitfalls in the methodology of these studies have led sometimes to misleading results
Our providers can help patients understand whether GLP-1 treatment may be appropriate, review possible risks and benefits, and explain the next steps when prior authorization is required
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