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As with GLP-1/GCG dual agonists, these triple agonists may have differential efficacy in non-alcoholic steatohepatitis, through reduction in energy intake, -oxidation, and de novo lipogenesis
Among the strategies: Sharipour agreed with these suggestions and emphasized the importance of a diet high in protein and fiber as well as daily aerobic and strength-building exercise
The recommendation: take calcium citrate (not calcium carbonate) if you're on a PPI, as citrate doesn't require acid for absorption
Step therapy can be waived with documented intolerance to phentermine, prior failure to lose weight on phentermine, or contraindication (cardiovascular disease, uncontrolled hypertension, seizure history)
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