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Meta-regression The meta-regression results indicated that the coefficient of MACE for metformin use was estimated as at 0.1436 (95%CI 0.0095, 0.2967), suggesting a potential positive effect of metformin on the outcome, but did not reach statistical significance ( P = 0.0661)

Metabolic & Cardiovascular Markers Across animal and human studies, researchers have tracked lipid profile shifts , cardiac function indicators , and immune-cell behavior linked to atherosclerotic plaque biology