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However, when cells become damaged beyond repair, cell death occurs
281 In the rat, The KD exacerbated disorders of glucose and lipid metabolisms and activated the renin-angiotensin-aldosterone system, 279 and the ketone body might reduce eNOS expression via NF-B singling pathway in vein endothelial cells, 280 which could collectively contribute to hypertension and endothelial dysfunction
[ref] Related article: GST Enzymes and Glutathione for Environmental Toxins UGT1A family and estrogenic mycotoxins (zearalenone, ochratoxin A): UGT1A1, UGT1A3, and UGT1A8 enzymes glucuronidate zearalenone, reducing its estrogenic activity and promoting excretion from the body
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