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10.1016/j.theriogenology.2004.09.014 218

The GLP-1 receptor agonist liraglutide improves memory function and increases hippocampal CA1 neuronal numbers in a senescence-accelerated mouse model of alzheimers disease

Furthermore, Nrf2/HO-1 interacts with the NF-KB and JAK-STAT pathways in various contexts: Nrf2/HO-1 can reduce NF-KB phosphorylation and thereby dampen inflammation, whereas proinflammatory cytokines such as TNF- and IL-6, released following NF-KB activation, upregulate HO-1 in a feedback loop (125, 129)

Questions to ask before treatment Do not proceed until you have satisfactory answers to these questions