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A treatment strategy based on stricter glucose control, intended to reduce glycated hemoglobin (HbA1c) levels to close to those of a person without diabetes, has been shown to reduce mortality and the appearance of micro- and macrovascular complications in people with DM (46)
Summary: Results from retatrutide typically become meaningful from months 36, with Phase 2 trial data showing continued weight loss through 48 weeks at higher doses
Interestingly, the significant weight loss many people experience with Ozempic may lead to some of the same complications as bariatric (weight loss) surgery
Kay LundJoel Habener-1GLP-1-2GLP-2 1980Svetlana MojsovGLP-1GLP-1MojsovGLP-131JGLP-1 Mojsov GLP-1GLP-1-1 1992John EngGila MonsterGLP-1Exendin-4 [22] 1996Amylin 2002Eli LillyAmylinExendin-4 2005FDAExendin-4Exenatide/ BYETTA/22BIDFirst-in-classGLP-1 2010FDAQD [] [] ^
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