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(2) Hashimotos thyroiditis leads to symptoms of hypothyroidism (or underactive thyroid), which may include: Weight gain Fatigue Sensitivity to cold temperatures Depression Problems concentrating Dry skin Brittle nails A puffy face Thinning hair Heavy or irregular menstrual periods Pain or swelling in the joints Constipation Muscle weakness Causes and Risk Factors of Hashimotos thyroiditis Doctors dont know exactly what causes Hashimoto's thyroiditis

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Some scholars believe that GLP-1RAs can promote the occurrence and development of tumors, mainly by facilitating tumor proliferation and inhibiting apoptosis, whereas others hold opposing viewpoints