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Inclusion criteria were as follows: Age 65 years with T2DM (according to ADA guidelines), Body mass index (BMI) 24kg/m, with no prior use of GLP-1RA or DPP-4 inhibitors
Frequently used in laboratory research involving anabolic signaling
The researchers found that subjects receiving just five low doses of MT-II (0.025 mg/kg) administered subcutaneously every other day experienced measurable increases in skin pigmentation
The FLOW trial [13], one of the few large-scale RCTs powered for a primary kidney endpoint, demonstrated significant reductions in major renal outcomes and slower eGFR decline in patients with T2D and CKD
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