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Tirzepatide builds on this foundation by simultaneously activating both GLP-1 and GIP receptors, potentially offering greater weight reduction for patients who plateau or seek enhanced results
Some people feel nothing at this dose
J Clin Endocrinol Metab 94(6):18431852
So while many IBS-D folks might see an improvement in diarrhoea, a subset could experience unpredictable bowel movements, especially during the initial weeks of therapy
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