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Comite also notes: Less common side effects include excess air or gas in the stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy, fatigue, and gallstones. Uncommon yet severe side effects also include: Pancreatitis Appendicitis Thyroid cancer Decreased kidney function Allergic reactions Anaphylaxis Angioedema If you experience any severe or unexpected symptoms, consult the clinician who prescribed the medication, Dr

Over-the-counter options like ondansetron (Zofran) and metoclopramide (Reglan) are commonly used alongside semaglutide, though you should confirm compatibility with your healthcare provider before starting either medication

Tirzepatide does not prevent this metabolic adaptation entirely, but the degree of slowdown may be less than with diet-only weight loss

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