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failure of tissues to respond to somatomedin, or failure of the liver to produce somatomedin
10.1111/dom.14908 Summary Keywords atrial fibrillation, atrial remodeling, epicardial adipose tissue, glucagon-like peptide-1 receptor agonist, therapeutic target Citation Liu L and Lu J (2026) Research on epicardial adipose tissue as a metabolic therapeutic target in AF: focus on GLP-1 receptor agonists
A Phase 1 Dose-Escalation Study of Milademetan in Combination with 5-Azacitidine (AZA) in Patients with Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndromes (MDS)
Further research identified GLP-1 in L cells of mammalian gut mucosa and later, it was proved that GLP-1 enhances insulin secretion in response to nutrient ingestion ( GLP-1 exerts physiological effects by binding to the GLP-1 receptor (GLP-1R) on target cells
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