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TEN significantly reduced glial fibrillary acidic protein immunoreactivity and astrocyte activation, implying that its analgesic effects are associated with suppression of spinal astrocytes and neuroinflammation [36, 37]

As ePA technology matures and becomes ubiquitous, we expect PAs for GLP-1s and other drugs to become increasingly seamless

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Other GPCR agonists have shown reliance upon the EGFR to activate PI3-kinase, including lysophosphatidic acid 29 , thrombin 30 , and angiotensin II 29

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