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The metathesis reaction was applied to obtain a series of macrocyclic compounds, devoid of the reactive disulfide function and with the potential to become oral bioavailable and more metabolically stable (Driggers et al., 2008

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Research Highlights Current research demonstrates: Significant reductions in pain scores Improved mobility and walking comfort Low complication rates Strong potential as a long-term alternative to surgery As clinical studies continue, PFE is gaining recognition nationwide as one of the most effective non-surgical options for chronic heel pain

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