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Cells were co-transfected with the following optimized donor:acceptor nanoBRET pair ratios: 50 ( 2A -AR-HaloTag): 1 (NanoLuc-G i1(91) or NanoLuc--arrestin2)
Frhbeck, G., Mndez-Gimnez, L., Fernndez-Formoso, J.-A., Fernndez, S
This slow ramp-up helps the body adjust and reduces the chance of digestive side effectsa strategy youd recognize if youre familiar with how Wegovy or Zepbound are dosed
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